On the characterization of sodium alginate/gelatine‐based hydrogels for wound dressing

Abstract

Abstract In this study, sodium alginate/gelatine (SA/G) hydrogels were prepared to obtain wound dressing with good, moist, healing, and biocompatibility properties. The physicochemical properties of hydrogels were evaluated by scanning electron microscopy, Fourier transform infrared spectroscopy, and a swelling test. Dynamic viscoelastic properties including the storage, loss moduli, G ′ and G ″, and loss angle, tan delta of both freshly prepared and swelled gels were examined in oscillatory experiments. Its results revealed that tested SA/G hydrogels exhibit highly elastic behavior similar to the viscoelastic response of human skin. Based on the performed analysis, it could be suggested that the SA/G hydrogel is a potential wound dressing material providing and maintaining the adequate moist environment required to prevent scab formation and the dehydration of the wound bed. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012