Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of <i>Leishmania donovani</i> - Concepedia

Concepedia

Publication | Closed Access

Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of <i>Leishmania donovani</i>

33

Citations

38

References

2015

Year

Bidyut Purkait, Ruby Singh, Kirti Wasnik, Sushmita Das, Ashish Kumar, Mark J. I. Paine, Manas Ranjan Dikhit, Dharmendra Singh, Abul Hasan Sardar, Ayan Kumar Ghosh,

Journal of Antimicrobial Chemotherapy

Abstract

Sir2 plays a critical role in AmB resistance by regulating MDR1, ROS concentration and apoptosis-like phenomena and may be a new resistance marker for visceral leishmaniasis.

References

	Year	Citations

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