CpG Island Methylation Is Responsible for <b> <i>p14ARF</i> </b> Inactivation and Inversely Correlates with p53 Overexpression in Resected Non–Small Cell Lung Cancer - Concepedia

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CpG Island Methylation Is Responsible for <b> <i>p14ARF</i> </b> Inactivation and Inversely Correlates with p53 Overexpression in Resected Non–Small Cell Lung Cancer

DOI Full Paper Access

37

Citations

27

References

2004

Year

Han‐Shui Hsu, Yu-Chien Wang, Ruo-Chia Tseng, Jer-Wei Chang, Jung-Ta Chen, Chuen-Ming Shih, Chih‐Yi Chen, Yi‐Ching Wang

Clinical Cancer Research

Abstract

Our data suggest that p14ARF 5'CpG hypermethylation is the predominant mechanism involved in the aberrant expression of the p14ARF gene. In addition, p14ARF 5'CpG hypermethylation occurs inversely to P53 overexpression.

References

	Year	Citations

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