Age-Dependent Normal Values of T2* and T2′ in Brain Parenchyma

Abstract

Decrease in T2' and T2* values in GM and increase of T2* values in WM correlate with the progress of brain aging. Explanations for decreasing T2' and T2* values include iron deposition in the caudate and lentiform nucleus. In contrast to T2* values, there is no association of T2' values with the degree of leukoaraiosis. These age-dependent values can be used as a reference in neurovascular diseases and for the discussion of functional MR imaging data.