Concepedia

Regioselective Synthesis of Multisubstituted Furans via Copper-Mediated Coupling between Ketones and β-Nitrostyrenes

Monoranjan Ghosh, Subhajit Mishra, Alakananda Hajra

The Journal of Organic Chemistry · 2015 · 79 citations · 40 references

DOI

Concepts

Abstract

A copper-mediated intermolecular annulation of alkyl ketones and β-nitrostyrenes has been developed for the regioselective synthesis of multisubstituted furan derivatives in good yields. This protocol is applicable to both cyclic and acyclic ketones.

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