Nanoparticle‐Based Energy Transfer for Rapid and Simple Detection of Protein Glycosylation

Abstract

Photoluminescence quenching of dextran-conjugated quantum dots (dex-QDs) by gold nanoparticles conjugated with concanavalin A (conA-AuNPs) can be prevented by adding a glycoprotein, which inhibits the association of dex-QDs with conA-AuNPs (see scheme). This phenomenon can be used as an analytical tool for the detection of protein glycosylation. PL=photoluminescence.