Publication | Open Access
Degradable cross-linked polymer vesicles for the efficient delivery of platinum drugs
28
Citations
21
References
2014
Year
NanotherapeuticsEngineeringBiomedical EngineeringEfficient DeliveryPlatinum DrugsNanomedicineOncologyDrug Delivery SystemDrug CarriersRadiation OncologyCancer ResearchPolymer ChemistryCell-based Drug DeliveryTumor TargetingPharmacologyBiomolecular EngineeringDrug TargetingPolymer-drug ConjugateDrug Delivery SystemsNano-drug DeliveryVesicle BiologyMedicineAcid-degradable Polymer VesiclesDrug-loaded Polymer Vesicles
Nontoxic and acid-degradable polymer vesicles were synthesized as drug carriers. <italic>In vitro</italic> dose–response cytotoxicity studies suggested that the drug-loaded polymer vesicles were more efficient in delivering cis-platin into cancer cells compared to the internalization of the free drug.
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