Concepedia

Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial

Paul Emery, Ferdinand C. Breedveld, Stephen Hall, Patrick Durez, David J. Chang, Deborah Robertson, Amitabh Singh, Ronald Pedersen, Andrew Koenig, Bruce Freundlich

The Lancet · 2008 · 817 citations · 34 references

DOI

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References

34

Modified disease activity scores that include twenty-eight-joint counts development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

M.L.L. Prevoo, Martin A. van't Hof, H. H. Kuper et al. · Arthritis & Rheumatism · 1995 · 6.2K citations

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The PREMIER study: A multicenter, randomized, double‐blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment

Ferdinand C. Breedveld, Michael H. Weisman, Arthur F. Kavanaugh et al. · Arthritis & Rheumatism · 2005 · 1.8K citations

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Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial

Lars Klareskog, Désirée van der Heijde, J Jäger et al. · The Lancet · 2004 · 1.8K citations

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Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): A randomized, controlled trial

Y P M Goekoop-Ruiterman, Jeska K de Vries‐Bouwstra, Cornelia F Allaart et al. · Arthritis & Rheumatism · 2005 · 1.5K citations · Full text

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Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial

Catriona Grigor, Hilary A. Capell, A. Stirling et al. · The Lancet · 2004 · 1.4K citations

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