Quantification of β-adrenoceptor density in the human heart with (S)-[11C]CGP 12388 and a tracer kinetic model

An Interior Trust Region Approach for Nonlinear Minimization Subject to Bounds

Thomas F. Coleman, Yuying Li · SIAM Journal on Optimization · 1996 · 3.3K citations

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A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

Mark A. Mintun, Marcus E. Raichle, Michael R. Kilbourn et al. · Annals of Neurology · 1984 · 963 citations

Medicine, Neuroscience, Pharmacology +17

On the Convergence of Reflective Newton Methods for Large-scale Nonlinear Minimization Subject to Bounds

Thomas F. Coleman, Yuying Li · eCommons (Cornell University) · 1992 · 559 citations · Full text

Natural Sciences, Computer Science, Mathematics +14

Simultaneous Determination of Beta-1 and Beta-2-Adrenergic Receptors in Tissues Containing Both Receptor Subtypes

Kenneth P. Minneman, Linda R. Hegstrand, Perry B. Molinoff · Molecular Pharmacology · 1979 · 421 citations

Medicine, Pharmacology, Biochemical Pharmacology +15

Comparison of Bolus and Infusion Methods for Receptor Quantitation: Application to [ ¹⁸ F]Cyclofoxy and Positron Emission Tomography

Richard E. Carson, Michael A. Channing, Ronald G. Blasberg et al. · Journal of Cerebral Blood Flow & Metabolism · 1993 · 381 citations

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