Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53 - Concepedia

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Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53

120

Citations

52

References

2009

Year

Tom Van Maerken, Liesbeth Ferdinande, Jasmien Taildeman, Irina Lambertz, Nurten Yigit, Liesbeth Vercruysse, Ali Rihani, Martin Michaelis, Jindřich Činátl, Claude Cuvelier,

JNCI Journal of the National Cancer Institute

Abstract

Nutlin-3 activates the p53 pathway and suppresses tumor growth in this model system of chemoresistant neuroblastoma, provided that wild-type p53 is present.

References

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