Supramolecular Iron Porphyrin/Cyclodextrin Dimer Complex that Mimics the Functions of Hemoglobin and Methemoglobin

Abstract

A real life saver: A supramolecule (met-hemoCD3, see scheme) was prepared by including a water-soluble porphinato iron(III) in a capsule of a cyclodextrin dimer (Py3OCD), which was synthesized in only two steps. The structure of met-hemoCD3 was determined by X-ray crystal analysis (see picture). Ferrous hemoCD3 showed functions similar to those of hemoglobin/myoglobin and also functioned as an antidote for cyanide poisoning. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.