Serum alanine aminotransferase predicts the histological course of non‐alcoholic steatohepatitis in <scp>J</scp>apanese patients

Abstract

A lack of reduction in serum ALT level by at least 30% from baseline was a predictor for histological progression in patients with NASH. Serum ALT level is a better predictor of histological change than insulin resistance or bodyweight and can be a valid index in treatment. Serum ALT should be strictly controlled to prevent liver histological progression in patients with NASH.