<i>MAPK14</i> and <i>CNR1</i> gene variant interactions: effects on brain volume deficits in schizophrenia patients with marijuana misuse

Abstract

Given that CNR1-induced apoptosis is preceded by increased MAPK phosphorylation, our study suggests that potential MAPK14-CNR1 gene-gene interactions may mediate brain morphometric features in schizophrenia patients with heavy marijuana use.