Effect of ursodeoxycholic acid on TGF beta1/Smad signaling pathway in rat hepatic stellate cells. - Concepedia

Concepedia

Publication | Closed Access

Effect of ursodeoxycholic acid on TGF beta1/Smad signaling pathway in rat hepatic stellate cells.

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References

2009

Year

Tie-Jun Liang, Junhua Yuan, Yan-Rong Tan, Wanhua Ren, Guoqing Han, Jie Zhang, Laicheng Wang, Chengyong Qin

Abstract

UDCA could curb the development of hepatic fibrosis through affecting the signaling pathway of TGFbeta1/Smad by inhibiting the expressions of TGFbeta1, Smad3 and CBP and increasing the expression of Smad7.