Chemistry Letters · 2008 · 44 citations · 23 references
Natural SciencesChemistryMedicinal ChemistryOrganic ChemistryHeterocycle SynthesisHeterocyclic Chemistry1, 3-Dipolar CycloadditionAsymmetric Heterocycle SynthesisAsymmetric SynthesisChiral Auxiliary Design
Abstract The asymmetric 1,3-dipolar cycloaddition of azomethine imines to allyl alcohol was achieved by utilizing diisopropyl (R,R)-tartrate as a chiral auxiliary to afford the corresponding optically active trans-pyrazolidines with excellent regio-, diastereo-, and enantioselectivities.
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