Concepedia

Publication | Open Access

Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice

DOIFull Paper Access

205

Citations

28

References

2012

Year

Mamdouh Sedhom, Mélanie Pichery, Jenna R. Murdoch, Benoît Foligné, Nathalie Ortéga, Sylvain Normand, Kirsten D. Mertz, Devika Sanmugalingam, L. Brault, Teddy Grandjean,
Gut

Abstract

Our study unveiled a novel non-hematopoietic function of IL-33 in epithelial barrier function and wound healing. Therefore, blocking the IL-33/ST2 axis may represent an efficient therapy in IBD.

References

YearCitations

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