Transfusion · 1999 · 33 citations · 17 references
MedicineGeriatric MedicineSurgeryPerioperative Quality ImprovementTransfusion MedicineVascular SurgeryAnemiaAutologous TransfusionBlood Transfusion ManagementBlood Transfusion SafetyDonor ManagementPerioperative Blood ManagementAllogeneic TransfusionContraindications To Autologous DonationPerioperative Blood Transfusion ManagementPreoperative Anemia ManagementPreoperative Autologous DonationSurgical Blood ManagementVasovagal Reaction PreventionVasovagal Reactions
BACKGROUND: Preoperative autologous blood donation (PABD) aims at avoiding the risks associated with exposure to allogeneic blood. While its use is extremely common among adult patients in connection with elective surgery, it is still uncommon in elderly patients, because of a series of coexisting pathologies. STUDY DESIGN AND METHODS: A retrospective study was made of 1073 consecutive elderly patients at a city hospital from 1990 to 1996. Their responses to the PABD program were evaluated by analysis of the incidence of complications and the demand for allogeneic blood. RESULTS: The PABD program was interrupted in 79 (7.4%) of 1073 patients because of the onset of anemia, vasovagal reactions, lack of accessible superficial veins, or cardiovascular complications. Seven hundred eighty-four (73.1%) of 1073 patients were given autologous blood; 151 (14.1%) patients also required allogeneic blood. CONCLUSION: The onset of anemia (6.5%) was the main contraindication for continuing the PABD program: incidence increased with age. PABD in connection with elective surgery is both feasible and effective in a high percentage of elderly patients.
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Predeposited Autologous Blood for Elective Surgery
Pearl T.G.V. Toy, Ronald G. Strauss, Linda C. Stehling et al. · New England Journal of Medicine · 1987 · 293 citations
Medicine, Hematology, Surgery +5
Effect of age on hematopoiesis in man
DA Lipschitz, KB Udupa, KY Milton et al. · Blood · 1984 · 193 citations · Full text
Medicine, Hematology, Pathobiology +10