Human recombinant erythropoietin inhibits interleukin-1 -stimulated nitric oxide and cyclic guanosine monophosphate production in cultured rat vascular smooth-muscle cells - Concepedia

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Human recombinant erythropoietin inhibits interleukin-1 -stimulated nitric oxide and cyclic guanosine monophosphate production in cultured rat vascular smooth-muscle cells

DOI Full Paper Access

31

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0

References

1999

Year

Eiji Kusano, Takayuki Akimoto, Makoto Inoue, Y. Masunaga, T. Umino, Shuichi Ono, Yukio Ando, Sumiko Homma, Shigeaki Muto, Norio Komatsu,

Nephrology Dialysis Transplantation

Abstract

It is suggested that a pharmacological dose of rHuEpo inhibits IL-1beta-induced NO and cGMP production as well as iNOS mRNA expression, presumably via the Epo receptor.