Impact of noninvasive home ventilation on long-term survival in chronic hypercapnic COPD: a prospective observational study

Abstract

In patients with severe chronic hypercapnic COPD receiving NIV at high inspiratory pressure levels and showing high adherence to this therapy, long-term survival was significantly higher than in non-ventilated patients. Patients displaying more severe disease according to known risk factors seemed to benefit most from long-term NIV.