Retrieval of trophoblast cells from the cervical canal for prediction of abnormal pregnancy: a pilot study

Abstract

This pilot study presents evidence that trophoblast cells can be reliably obtained and identified among cervical cells in the first trimester by immunohistochemical staining for HLA-G, and suggests for the first time that abnormal pregnancies may be predictable based on the abundance of trophoblast cells in the cervical canal.