Efficient Synthesis of Chiral α‐ and β‐Hydroxy Amides: Application to the Synthesis of (<i>R</i>)‐Fluoxetine

Abstract

Four flavors for epoxide openings: The regioselective openings of epoxy amides obtained by asymmetric epoxidation yields all types of aryl- and alkyl-substituted hydroxy amides sometimes counter to the reactivity of the α- and β-positions. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z52431_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.