Concepedia

Synthesis and novel structure–activity relationships of potent sansalvamide A derivatives

Katerina Otrubova, Thomas J. Styers, Po‐Shen Pan, Rodrigo A. Rodriguez, Kathleen L. McGuire, Shelli R. McAlpine

Chemical Communications · 2006 · 26 citations · 7 references

DOI

Concepts

Abstract

Synthesis of twelve Sansalvamide A derivatives and their SAR against colon cancer (HT-29).

References

7

Sansalvamide: A new cytotoxic cyclic depsipeptide produced by a marine fungus of the genus Fusarium

Gilbert N. Belofsky, Paul R. Jensen, William Fenical · Tetrahedron Letters · 1999 · 150 citations

, , +16

Mechanism of Inhibition of a Poxvirus Topoisomerase by the Marine Natural Product Sansalvamide A

Young Sun Hwang, David Rowley, Denise Rhodes et al. · Molecular Pharmacology · 1999 · 105 citations

, , +14

<i>N</i>-Methylsansalvamide A Peptide Analogues. Potent New Antitumor Agents

Shouxin Liu, Wenxin Gu, Denise J. Lo et al. · Journal of Medicinal Chemistry · 2005 · 83 citations

, , +14

N-Methylsansalvamide, a cytotoxic cyclic depsipeptide from a marine fungus of the genus Fusarium

Mercedes Cueto, Paul R. Jensen, William Fenical · Phytochemistry · 2000 · 71 citations

, , +15

Rapid, High-Yield, Solid-Phase Synthesis of the Antitumor Antibiotic Sansalvamide A Using a Side-Chain-Tethered Phenylalanine Building Block

Younghee Lee, Richard B. Silverman · Organic Letters · 2000 · 39 citations

, , +17