Journal of Obstetrics and Gynaecology · 2011 · 35 citations · 9 references
MedicineGynecologySurgeryGeneral SurgeryReconstructive SurgeryUrodynamicsOutcome AssessmentPelvic Floor DisordersPelvic Floor ReconstructionPelvic Organ ProlapsePelvic Organ Prolapse SurgeryReconstructive Pelvic SurgeryFunctional Outcomes After Prolapse RepairFunctional Outcomes After Prolapse SurgeryMesh-based Prolapse RepairPelvic Floor Mesh RepairPelvic Organ Prolapse SymptomatologyPostoperative Urinary IncontinenceSexual Function After Prolapse SurgeryUrinary Incontinence After Prolapse Surgery
The effects at 2 years of polyglactin (Vicryl) mesh inlay and polydioxanone (PDS) or polyglactin (Vicryl) suture material on prolapse symptoms, urinary, bowel, sexual function and prolapse related Quality-of-Life (QoL) in women undergoing pelvic organ prolapse surgery were evaluated in a randomised controlled trial with a 2 × 2 factorial design of Vicryl mesh (n = 32) or not (n = 34) and PDS (n = 33) or Vicryl suture (n = 33). The response rate at 2 years was 82%. There were no differences in the prolapse symptom scores between the randomised groups. Prolapse-related QoL score (mean difference: 2.05, 95% CI 0.19-3.91) and urinary incontinence score (mean difference: 2.56, 95% CI 0.02-5.11) were significantly lower (better) in women who had Vicryl compared with PDS sutures. The apparent superiority of the prolapse-related QoL and urinary incontinence scores in women using Vicryl suture material (vs PDS) needs to be confirmed in a larger trial.
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Cochrane Database of Systematic Reviews
Progress in Neurology and Psychiatry · 2011 · 4.7K citations · Full text
Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence
Adam S. Olsen, Vincent C. Smith, Jonas Bergström et al. · Obstetrics and Gynecology · 1997 · 3.4K citations