<i>NQO1</i> and <i>NFE2L2</i> polymorphisms, fruit and vegetable intake and smoking and the risk of colorectal adenomas in an endoscopy‐based population

Abstract

the NQO1 609CT genotype is associated with increased adenoma risk among smokers, which is not diminished by high fruit and vegetable consumption. The observed gene-gene interactions may point to a role for NFE2L2 polymorphisms in NQO1-related adenoma formation.