Concepedia

A Darwinian approach to Huntington’s disease: Subtle health benefits of a neurological disorder

Benjamin R. Eskenazi, Noah Wilson-Rich, Philip T. Starks

Medical Hypotheses · 2007 · 27 citations · 56 references

DOI

Concepts

References

56

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

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Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

, , +17

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations

, , +17

Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence

Akinori Takaoka, Sumio Hayakawa, Hideyuki Yanai et al. · Nature · 2003 · 846 citations

, , +16

Evolution of infectious disease

Choice Reviews Online · 1994 · 731 citations

, , +17