High Risk of Neutropenia in HIV‐Infected Children following Treatment with Artesunate plus Amodiaquine for Uncomplicated Malaria in Uganda

Abstract

Artesunate plus amodiaquine was highly efficacious for malaria treatment in HIV-infected children but was associated with a high risk of neutropenia, especially in the context of concurrent antiretroviral use. Our findings highlight an urgent need for evaluation of alternative antimalarial therapies for HIV-infected individuals.