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An enantioselective, stereodivergent approach to anti- and syn-α-hydroxy-β-amino acids from anti-3-amino-1,2-diols. Synthesis of the ready for coupling taxotere® side chain.

Taxotere® Side ChainEngineeringDiversity-oriented SynthesisSyn-α-hydroxy-β-amino AcidsOrganic ChemistryStereodivergent ApproachStereoselective SynthesisPharmacologyAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering