Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities

A therapeutic vaccine for nicotine dependence: preclinical efficacy, and phase I safety and immunogenicity

Patrik Maurer, Gary T. Jennings, Jörg Willers et al. · European Journal of Immunology · 2005 · 280 citations · Full text

Medicine, Immunology, Pharmacology +17

Cocaine Vaccine for the Treatment of Cocaine Dependence in Methadone-Maintained Patients

Bridget Martell, Frank M. Orson, James Poling et al. · Archives of General Psychiatry · 2009 · 263 citations · Full text

Veterinary Medicine, Pharmacology, Immunization +12

Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: Absence of an isotope effect in the clearance of (S)-nicotine-3′,3′-d2 in humans

Peyton Jacob, Lisa Yu, Margaret D. Wilson et al. · Journal of Mass Spectrometry · 1991 · 237 citations

Pharmacy, Chemistry, Pharmacokinetics +16

Immunogenicity and Smoking-Cessation Outcomes for a Novel Nicotine Immunotherapeutic

Dorothy K. Hatsukami, Douglas E. Jorenby, David Gonzales et al. · Clinical Pharmacology & Therapeutics · 2011 · 185 citations · Full text

Veterinary Medicine, Immunology, Pharmacology +17

A Nicotine Conjugate Vaccine Reduces Nicotine Distribution to Brain and Attenuates Its Behavioral and Cardiovascular Effects in Rats

Paul R. Pentel, David H. Malin, Sofiane Ennifar et al. · Pharmacology Biochemistry and Behavior · 2000 · 180 citations

Medicine, Neuroscience, Pharmacology +10