Addiction · 2008 · 30 citations · 13 references
MedicinePharmacologyPharmacotherapyClinical PharmacologyPharmacovigilancePsychopharmacologyAdverse Drug Event PreventionRational PrescribingMethadone Maintenance TherapyMethadone Maintenance TreatmentMethadone ToxicologyQt Interval AnalysisQt Interval Assessment
ABSTRACT Background Methadone has been associated with QT prolongation and Torsades de pointes. Ciprofloxacin may prolong QT interval and induce Torsades de pointes when other risk factors are present. Case description A case is described in which a patient receiving methadone treatment developed Torsades de pointes following the addition of ciprofloxacin. Conclusion Ciprofloxacin should be used with caution in patients receiving methadone.
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Torsade de Pointes Associated with Very-High-Dose Methadone
Mori J. Krantz, Laurent Lewkowiez, Helen Hays et al. · Annals of Internal Medicine · 2002 · 424 citations
Drug-Induced Long QT Syndrome in Injection Drug Users Receiving Methadone
Georg Ehret, Cathy Voide, Marianne Gex‐Fabry et al. · Archives of Internal Medicine · 2006 · 228 citations · Full text