Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease - Concepedia

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Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease

DOI Full Paper Access

65

Citations

45

References

2011

Year

Lars P. Bechmann, Amalia Gastaldelli, Diana Vetter, Gillian Patman, Laura Pascoe, Rebekka A. Hannivoort, Ursula E. Lee, Isabel Fiel, Úrsula Muñoz, Demetrio Ciociaro,

Abstract

KLF6 regulation of GCK contributes to the development of hepatic insulin resistance. The KLF6-IVS1-27A polymorphism, which generates more KLF6-SV1, combats this, lowering hepatic insulin resistance and blood glucose.

References

	Year	Citations

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