Complex systems biology approach to understanding coordination of JAK-STAT signaling

From molecular to modular cell biology

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Cell Division, Cell Organelle, Multicellular System +5

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention.

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Signal Transducers, Immunology, Particular Stat3 +18

Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway

Min You, Dehua Yu, Gen‐Sheng Feng · Molecular and Cellular Biology · 1999 · 359 citations · Full text

Negative Regulator, Molecular Regulation, Immunology +19

Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by databased modeling

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The Jak-Stat pathway in normal and perturbed hematopoiesis

Alister C. Ward, Ivo P. Touw, Akihiko Yoshimura · Blood · 2000 · 295 citations