Chemical and Pharmaceutical Bulletin · 2003 · 17 citations · 15 references
Natural SciencesChemistryMedicinal ChemistryDrug DiscoveryOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryHeterocyclic CompoundsMacrocycle SynthesisOrganic SynthesisSteroid StructureBicyclononyne ChemistryStereochemical Requirements
A new route to (+)-estrone has been developed starting from the chiral building block having a bicyclo[3.2.1]octane framework based on the inherent stereochemical chemical nature of the chiral building block.
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Gary H. Posner, Christopher Switzer · Journal of the American Chemical Society · 1986 · 81 citations