Infection and Immunity · 1994 · 108 citations · 23 references
Veterinary MedicineInfectious DiseasesMicrobiologyHost-pathogen InteractionsImmunology Of Infectious DiseasesParasitologyHost-parasite Immune InteractionsHost-parasite InteractionsParasitic Disease PathogenesisParasitic PathogenesisParasitic PathologyRodent Infectious DiseasesAntigenic Variation In VirusesGiardiasis PathogenesisParasite Antigenic VariationParasite-immune Interactions
An adult mouse-Giardia lamblia model was developed and used to study host-parasite interactions, including antigenic variation. The H7/1 clone of isolate GS infected mice consistently and produced infections in 14 mouse strains tested. Infection patterns were mouse strain and Giardia isolate dependent. Antigenic variation occurred in immunocompetent mice but not in mice with severe combined immunodeficiency.
23
Giardiasis in the Mouse: An Animal Model
Ian C. Roberts‐Thomson, David Stevens, Adel A. F. Mahmoud et al. · Gastroenterology · 1976 · 325 citations