European Journal of Endocrinology · 2008 · 138 citations · 34 references
Letrozole 2.5 mg once a week produced a sustained normalization of serum total testosterone in obese men with IHH. However, free testosterone frequently rose to supraphysiological levels. Therefore, a starting dose <2.5 mg once a week is recommended.
34
Effect of Testosterone and Estradiol in a Man with Aromatase Deficiency
Cesare Carani, Kenan Qin, Manuela Simoni et al. · New England Journal of Medicine · 1997 · 1.2K citations · Full text