Concepedia

Formal synthesis of (±)-platensimycin

K. C. Nicolaou, Yefeng Tang, Jianhua Wang

Chemical Communications · 2007 · 103 citations · 10 references

DOI

Concepts

Abstract

A formal total synthesis of (+/-)-platensimycin [(+/-)-1] is reported involving an intramolecular Stetter reaction and a radical cyclization.

References

10

Nucleophilic Carbenes in Asymmetric Organocatalysis

Dieter Enders, Tim Balensiefer · Accounts of Chemical Research · 2004 · 1K citations

, , +14

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, S.M. Soisson, Katherine Young et al. · Nature · 2006 · 815 citations

, , +9

Asymmetric Synthesis of Hydrobenzofuranones via Desymmetrization of Cyclohexadienones Using the Intramolecular Stetter Reaction

Qin Liu, Tomislav Rovis · Journal of the American Chemical Society · 2006 · 296 citations · Full text

, , +5

An Efficient Synthesis of Achiral and Chiral 1,2,4-Triazolium Salts:  Bench Stable Precursors for N<i>-</i>Heterocyclic Carbenes

Mark S. Kerr, Javier Read de Alaniz, Tomislav Rovis · The Journal of Organic Chemistry · 2005 · 267 citations · Full text

, , +13

A Highly Enantio- and Diastereoselective Catalytic Intramolecular Stetter Reaction

Javier Read de Alaniz, Tomislav Rovis · Journal of the American Chemical Society · 2005 · 250 citations

, , +12