Glycine site <i>N</i>-methyl-<scp>d</scp>-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats

Abstract

Our findings demonstrate that acute 7-CTKA administration produced rapid antidepressant-like effects, indicating that the behavioural response to 7-CTKA is mediated by GSK3β and mTOR signalling function in the mPFC.