Variability in Absolute Apparent Diffusion Coefficient Values across Different Platforms May Be Substantial: A Multivendor, Multi-institutional Comparison Study

Abstract

There is significant variability in ADC values depending on the coil systems, imagers, vendors, and field strengths used for MR imaging. The relative ADC values may be more suitable than absolute ADC values for evaluating diffusion abnormalities in patients enrolled in multicenter acute ischemic stroke trials.