Kidney tubular damage in the absence of glomerular defects in HIV-infected patients on highly active antiretroviral therapy

Abstract

A quarter of HIV-infected patients receiving HAART had subclinical tubular damage, which was associated with a near-term decline in eGFR and higher incidence of proteinuria. Periodic monitoring of urinary biomarkers might facilitate the early identification of HAART patients predisposed to significant kidney disease.