Concepedia

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells

Shunji Chi, Chifumi Kitanaka, Kohji Noguchi, Toshihiro Mochizuki, Yohji Nagashima, Mikako Shirouzu, Hideaki Fujita, Midori Yoshida, Wenbin Chen, Akio Asai,

Oncogene · 1999 · 251 citations · 25 references

DOI

Concepts

References

25

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Hartmut Land, Luis F. Parada, Robert A. Weinberg · Nature · 1983 · 2.9K citations

, , +16

Phosphatidylinositol-3-OH kinase direct target of Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Ritu Dhand et al. · Nature · 1994 · 1.9K citations

, , +12

Role of the INK4a Locus in Tumor Suppression and Cell Mortality

Manuel Serrano, Han‐Woong Lee, Lynda Chin et al. · Cell · 1996 · 1.6K citations · Full text

, , +16

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

Per O. Seglen, Paul B. Gordon · Proceedings of the National Academy of Sciences · 1982 · 1.3K citations · Full text

, , +15