Increased (CTG/CAG)n lengths in myotonic dystrophy type 1 and Machado–Joseph disease genes in idiopathic azoospermia patients

Abstract

These data indicated that, at least in a subset of azoospermia patients, there was an increase in the number of trinucleotide repeats in some disease loci. Thus, it is noteworthy to evaluate whether offspring of these azoospermia patients, if born by assisted reproductive technologies, have an increased risk of trinucleotide repeat diseases.