Radiographic Screening of Infants and Young Children With Genetic Predisposition for Rare Malignancies: <i>DICER1</i> Mutations and Pleuropulmonary Blastoma

Abstract

Even for a rare disease such as pleuropulmonary blastoma, radiographic screening of infants and young children with cancer-predisposing mutations may result in improved life expectancy compared with the unscreened population. The benefit of screening will be greater for diseases with a higher screening yield.