Concepedia

The Spinal Cord in Multiple Sclerosis: Relationship of High-Spatial-Resolution Quantitative MR Imaging Findings to Histopathologic Results

Joost Bot, Erwin L. A. Blezer, Wouter Kamphorst, Geert J. Lycklama à Nijeholt, Herman J. Adèr, Jonas A. Castelijns, Klaas Nicolay Ig, Elisabeth Bergers, Rivka Ravid, Chris H. Polman,

Radiology · 2004 · 142 citations · 24 references

DOI

Abstract

Changes in quantitative MR imaging parameters in the cervical spinal cord in MS are mainly determined by demyelination and do not reflect axonal disease well.

References

24

Axonal loss in multiple sclerosis lesions: Magnetic resonance imaging insights into substrates of disability

J.H.T.M. van Waesberghe, W. Kamphorst, Corline J.A. De Groot et al. · Annals of Neurology · 1999 · 729 citations

Neurological Disorder, White Matter, Neurological Progress +18

Spinal cord atrophy and disability in multiple sclerosis

N. A. Losseff, Stephen A. Webb, J O’Riordan et al. · Brain · 1996 · 634 citations · Full text

Brain and spinal cord abnormalities in multiple sclerosis. Correlation between MRI parameters, clinical subtypes and symptoms

G. Nijeholt · Brain · 1998 · 378 citations · Full text

Spinal Cord Injury, Neurological Disorder, Spinal Cord Abnormalities +12

Axonal changes in chronic demyelinated cervical spinal cord plaques

Gábor Lovas, Nóra Szilágyi, Katalin Majtényi et al. · Brain · 2000 · 356 citations · Full text

Histopathologic correlates of white matter changes on MRI in Alzheimer's disease and normal aging

Philip Scheltens, Frederik Barkhof, Didier Leys et al. · Neurology · 1995 · 345 citations