Concepedia

Overexpression of Uncoupling Protein 2 in THP1 Monocytes Inhibits β <sub>2</sub> Integrin-Mediated Firm Adhesion and Transendothelial Migration

Je-Won Ryu, Kyung Hee Hong, Jin Hee Maeng, Jae Bum Kim, Jesang Ko, Joong Yeol Park, Ki‐Up Lee, Myeong‐Ki Hong, Seong Wook Park, You Ho Kim,

Arteriosclerosis Thrombosis and Vascular Biology · 2004 · 61 citations · 17 references

DOIFull text

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Abstract

Mitochondrial UCP2 in circulating monocytes may prevent excessive accumulation of monocytes/macrophages in the arterial wall, thereby reducing atherosclerotic plaque formation.

References

17

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

Denis Arsenijevic, Hiroki Onuma, Claire Pecqueur et al. · Nature Genetics · 2000 · 1.1K citations

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Chemokines and the Arrest of Lymphocytes Rolling Under Flow Conditions

James J. Campbell, Joseph A. Hedrick, Albert Zlotnik et al. · Science · 1998 · 988 citations

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A role for uncoupling protein‐2 as a regulator of mitochondrial hydrogen peroxide generation

Anne Nègre‐Salvayre, Christophe Hirtz, G. Carrera et al. · The FASEB Journal · 1997 · 765 citations

, , +16

The combined role of P- and E-selectins in atherosclerosis.

Zhao Dong, Susan M. Chapman, Andrew Brown et al. · Journal of Clinical Investigation · 1998 · 451 citations · Full text

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Uncoupling Protein-2 Overexpression Inhibits Mitochondrial Death Pathway in Cardiomyocytes

Yasushi Teshima, Masaharu Akao, Steven P. Jones et al. · Circulation Research · 2003 · 312 citations · Full text

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