Abstract We provide a detailed, introductory exposition of the Metropolis-Hastings algorithm, a powerful Markov chain method to simulate multivariate distributions. A simple, intuitive derivation of this method is given along with guidance on implementation. Also discussed are two applications of the algorithm, one for implementing acceptance-rejection sampling when a blanketing function is not available and the other for implementing the algorithm with block-at-a-time scans. In the latter situation, many different algorithms, including the Gibbs sampler, are shown to be special cases of the Metropolis-Hastings algorithm. The methods are illustrated with examples. Key Words: Gibbs samplingMarkov chain Monte CarloMultivariate density simulationReversible Markov chains