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A Simple and Highly Selective Biomimetic Oxidation of Alcohols and Epoxides with <i>N</i>‐Bromosuccinimide in the Presence of β‐Cyclodextrin in Water
85
Citations
10
References
2004
Year
Room TemperatureChemical EngineeringVarious AlcoholsBioorganic ChemistryEngineeringAdvanced Oxidation ProcessNatural SciencesCyclodextrin ProductionDiversity-oriented SynthesisOrganic ChemistryN ‐BromosuccinimideCatalysisChemistry
Abstract A simple, mild and highly efficient biomimetic oxidation of various alcohols and epoxides with N ‐bromosuccinimide (NBS) catalyzed by β‐cyclodextrin in water has been developed. A series of alcohols and epoxides were oxidized selectively at room temperature in excellent yields. This method is a direct one‐pot synthesis under mild conditions using water as solvent and has many advantages over the existing methodologies.
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