Concepedia

Pharmacokinetics and Metabolic Profile of Free, Conjugated, and Total Silymarin Flavonolignans in Human Plasma after Oral Administration of Milk Thistle Extract

Zhiming Wen, Todd Dumas, Sarah J. Schrieber, Roy L. Hawke, Michael Fried, Philip Coleridge Smith

Drug Metabolism and Disposition · 2007 · 171 citations · 18 references

DOI

Concepts

References

18

Pharmacology of Silymarin

F. Fraschini, G. Demartini, D. Esposti · Clinical Drug Investigation · 2002 · 381 citations

Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum)Electronic supplementary information (ESI) available: HPLC chromatograms of isolates and extracts. See http://www.rsc.org/suppdata/ob/b3/b300099k/

Nam-Cheol Kim, Tyler N. Graf, Charles M. Sparacino et al. · Organic & Biomolecular Chemistry · 2003 · 278 citations

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Molecular Structure and Stereochemistry of Silybin A, Silybin B, Isosilybin A, and Isosilybin B, Isolated from <i>Silybum </i><i>m</i><i>arianum</i> (Milk Thistle)

David Y.W. Lee, Liu · Journal of Natural Products · 2003 · 248 citations

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Pharmacokinetic studies on IdB 1016, a silybin-phosphatidylcholine complex, in healthy human subjects

N. Barzaghi, Francesca Crema, G. Gatti et al. · European Journal of Drug Metabolism and Pharmacokinetics · 1990 · 223 citations

, , +4

Protection by silibinin against Amanita phalloides intoxication in beagles

G Vogel, Béatriz Tuchweber, W Trost et al. · Toxicology and Applied Pharmacology · 1984 · 169 citations

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