Scolecite as a Novel Heterogeneous Acid Catalyst for an Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Via Multi-component Biginelli Reaction

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

Molecular Biology, Small Molecule Inhibitor, Cytoskeleton +18

Asymmetric Multicomponent Reactions (AMCRs): The New Frontier

Diego J. Ramón, Miguel Yus · Angewandte Chemie International Edition · 2005 · 1.7K citations

Chemical Engineering, Cross-coupling Reaction, Engineering +14

100 years of the biginelli dihydropyrimidine synthesis

C. Oliver Kappe · Tetrahedron · 1993 · 1.2K citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +3

Unprecedented Catalytic Three Component One-Pot Condensation Reaction:  An Efficient Synthesis of 5-Alkoxycarbonyl- 4-aryl-3,4-dihydropyrimidin-2(1H)-ones

Essa Hu, Daniel R. Sidler, Ulf‐H. Dolling · The Journal of Organic Chemistry · 1998 · 498 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +11

Ionic liquids catalyzed Biginelli reaction under solvent-free conditions

Jiajian Peng, Youquan Deng · Tetrahedron Letters · 2001 · 341 citations

Chemical Engineering, Engineering, Ionic Liquids +5