Concepedia

Pathways of Carbamazepine Bioactivation in Vitro. III. The Role of Human Cytochrome P450 Enzymes in the Formation of 2,3-Dihydroxycarbamazepine

Robin E. Pearce, Wei Lü, Yongqiang Wang, Jack Uetrecht, Maria Almira Correia, J. Steven Leeder

Drug Metabolism and Disposition · 2008 · 99 citations · 42 references

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Concepts

References

42

Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk.

Neil H. Shear, S P Spielberg · Journal of Clinical Investigation · 1988 · 689 citations · Full text

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Anticonvulsant Hypersensitivity Syndrome

Carmela C. Vittorio · Archives of Internal Medicine · 1995 · 423 citations

, , +15

Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site

Magang Shou, James Grogan, Julie Mancewicz et al. · Biochemistry · 1994 · 350 citations

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Expression of Modified Human Cytochrome P450 3A4 in Escherichia coli and Purification and Reconstitution of the Enzyme

Elizabeth M. J. Gillam, T. Baba, Bok‐Ryang Kim et al. · Archives of Biochemistry and Biophysics · 1993 · 347 citations

, , +14

Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: A record linkage study

Patricia Tennis, Robert S. Stern · Neurology · 1997 · 259 citations

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