Increase in visceral and subcutaneous abdominal fat in men with prostate cancer treated with androgen deprivation therapy

Abstract

ADT for prostate cancer results in accumulation of both visceral and subcutaneous abdominal fat. Increased visceral fat area appears more closely linked to testosterone than oestradiol deficiency. Increased insulin resistance may arise secondary to visceral fat accumulation, rather than as a direct result of sex steroid deficiency.