Concepedia

31P magnetic resonance spectroscopy in dilated cardiomyopathy and coronary artery disease. Altered cardiac high-energy phosphate metabolism in heart failure.

Stefan Neubauer, Thomas E. Krahe, R Schindler, M. Horn, Hanns B. Hillenbrand, C. Entzeroth, H Mader, Eckhard P. Kromer, Günter A.J. Riegger, K. Lackner

Circulation · 1992 · 381 citations · 29 references

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Abstract

Cardiac high-energy phosphate metabolism at rest is normal in LAD stenosis and chronic myocardial infarction in the absence of heart failure. The CP/ATP ratio has low specificity for the diagnosis of dilated cardiomyopathy. However, CP/ATP correlated with the clinical severity of heart failure and may improve during clinical recompensation.

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Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy

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Altered myocardial high-energy phosphate metabolites in patients with dilated cardiomyopathy

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